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目的 观察异体组织埋藏法治疗视网膜色素变性的近期及中远期疗效。方法 随访26例(52眼)接受异体组织埋藏法治疗视网膜色素变性患者;术前、术後12周、术後6月和术後1年分别检查视力、视野。结果 术後近期(12周)患者视力显著提高(X~2=11.02,P<0.05),术後6月患者视力无继续提高(X~2=0.31,P>0.05),术後一年患者视力亦无继续改善(X~2=0.83,P>0.05);术後近期(12周)视野较术前明显扩大(X~2=7.90,P<0.05),术後6月视野与术後12周视野相比无明显改善(X~2=1.14,P>0.05),术後一年视野和术後12周视野相比有进步,但无统计学意义(X~2=0.42,P>0.05)。结论 异体组织埋藏法治疗视网膜色素变性近期(12周)具有肯定疗效;中远期(6～12月)疗效稳定。
Objective To observe the short-term and long-term therapeutic effects of allogeneic tissue burial in the treatment of retinitis pigmentosa. Methods Follow-up 26 cases (52 eyes) underwent allogeneic burial in patients with retinitis pigmentosa. Visual acuity and visual field were examined before operation, 12 weeks after operation, 6 months after operation and 1 year after operation. Results The visual acuity (X ~ 2 = 11.02, P <0.05) of patients in the short term after operation (12 weeks) was significantly higher than that in the patients after operation (P <0.05) (X ~ 2 = 0.83, P> 0.05). The visual field in the short term (12 weeks) after surgery was significantly increased (X ~ 2 = 7.90, P <0.05) There was no significant difference between 12 and 12 weeks visual field (X ~ 2 = 1.14, P> 0.05) 0.05). Conclusion Allogeneic tissue burial treatment of retinitis pigmentosa recent (12 weeks) has a positive effect; long-term (6 ~ December) and stable.