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采用脑脉舒宁提取液（1ml相当于生药0．5g）以50％和25％浓度分别对两组食高脂饲料的大鼠进行灌胃，对照组为生理盐水。每次10．0ml／kg，每日1次，连用10天，于实验第11天对3组大鼠进行断头取血。测定其血胆固醇、甘油三酯和血浆粘度。结果显示：高浓度（50％）给药组大鼠的血胆固醇、甘油三酯和血浆粘度均下降，与对照组比较有显著性差异（P＜0．05和P＜0．01）；而低浓度（25％）给药组大鼠仅血浆粘度显著下降（P＜0．01）。给药前后各级大鼠的体重、饮水和饮食量无明显差异。每组大鼠胸主动脉和冠状动脉病理切片无粥样硬化病变产生。
Two groups of rats fed with high-fat diet were intragastrically administrated with Naoshunsuoning extract (1ml equivalent to 0.5g crude drug) in 50% and 25% concentrations, respectively. The control group was given normal saline. Each 10.0ml / kg, once daily, once every 10 days, on the 11th day of experiment on the three groups of rats were decapitated. Determination of blood cholesterol, triglycerides and plasma viscosity. The results showed that the blood cholesterol, triglyceride and plasma viscosity of rats in high concentration (50%) group decreased significantly compared with the control group (P <0.05 and P <0.01) Only the plasma viscosity of rats in low concentration (25%) group decreased significantly (P <0.01). Before and after administration of rats at all levels of body weight, drinking water and diet no significant difference. Thoracic aorta and coronary artery pathology in each group of atherosclerosis lesions.