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以中药黄芪、丹参注射液加入体外分散培养乳鼠之SC培养液中,观察二种药物的三个浓度对细胞生长的影响。结果:黄芪(50mg/ml、200mg/ml、500mg/ml三种浓度)对体外培养SC未见明显的毒性作用;其中中等浓度对SC有轻度的促增殖作用;丹参在低于3mg/ml时,SC生长良好,高于6mg/ml时,细胞变圆、生长不良。提示:较高浓度的丹参注射液对培养的SC具有一定的毒性作用;而中等浓度(200mg/ml)的黄芪注射液对培养的SC具轻度的促增殖作用。
The effects of three concentrations of two drugs on the cell growth were observed by adding the Chinese herbal medicine Huangqi and Salvia miltiorrhiza injection to the cultured SC culture medium of the suckling mice. Results: Astragalus membranaceus (50mg/ml, 200mg/ml, 500mg/ml three concentrations) had no obvious toxic effect on SC cultured in vitro; among them, moderate concentration had slight proliferative effect on SC; salvia miltiorrhiza was lower than 3mg/ml At the time, the SC grew well. Above 6 mg/ml, the cells became round and the growth was poor. Tip: Higher concentrations of Danshen injection have a certain toxic effect on the cultured SC, while medium concentration (200mg/ml) of Astragalus injection has a slight pro-proliferation effect on cultured SC.