植物细胞内抗病蛋白特异性识别病原菌后激发强烈的抗病反应,这类抗病反应往往伴有局部的细胞死亡。但抗病蛋白介导的抗病与细胞死亡的因果关系多有争议,其亚细胞分区定位与死亡信号的关系也不是很清楚。中科院遗传与发育生物学研究所沈前华课题组系统地研究了大麦白粉菌抗病蛋白MLA10结构与功能的关系,亚 Plant-specific anti-phytoplasma proteins recognize pathogenic bacteria and stimulate a strong disease-resistant response, such resistance is often accompanied by local cell death. However, the causal relationship between disease-resistant protein-mediated resistance and cell death is controversial. The relationship between subcellular localization and signal of death is not clear. Shen Qian Institute of Genetics and Developmental Biology, Chinese Academy of Sciences research group systematically studied the relationship between structure and function of powdery mildew resistant disease protein MLA10,