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目的:观察超声药物导入结合中药保留灌肠治疗慢性盆腔炎的疗效。方法:采用随机数表法、对照的原则,将80例慢性盆腔炎患者随机分为观察组和对照组各40例,其中观察组应用超声药物导入结合中药保留灌肠治疗,对照组仅予中药保留灌肠治疗。结果:(1)2组临床总有效率比较差异有统计学意义(P<0.05)。(2)两组治疗前后病情评分差值比较,差异有统计学意义(P<0.01)。(3)治疗后两组IL-2值水平升高,TNF-α水平下降,与治疗前比较,差异有明显统计学意义(P<0.01)。(4)治疗后观察组IL-2水平高于对照组,TNF-α水平低于对照组,差异有统计学意义(P<0.01)。结论:利用超声药物导入法配合传统中药保留灌肠的中西医结合的方法疗效明显优于单一药物疗法,且进一步提示慢性盆腔炎的发病与患者免疫功能状态密切相关,免疫学指标的检测或可以揭示综合干预疗法的作用机制。
OBJECTIVE: To observe the curative effect of ultrasonic drug introduction combined with traditional Chinese medicine retention enema in the treatment of chronic pelvic inflammatory disease. Methods: Using random number table method and control principle, 80 patients with chronic pelvic inflammatory disease were randomly divided into the observation group and the control group, 40 cases in each group. The observation group was treated with ultrasound and imported Chinese medicine retention enema. Enema treatment. Results: (1) The total effective rate of the two groups was statistically significant (P <0.05). (2) There was significant difference between the two groups before and after treatment (P <0.01). (3) The level of IL-2 and the level of TNF-αdecreased in both groups after treatment, the difference was statistically significant (P <0.01). (4) After treatment, the level of IL-2 in the observation group was higher than that in the control group, and the level of TNF-α was lower than that in the control group (P <0.01). Conclusion: The combination of traditional Chinese medicine and traditional Chinese medicine enema with traditional Chinese medicine is superior to single drug therapy in the treatment of traditional Chinese medicine enema, and further suggests that the incidence of chronic pelvic inflammatory disease is closely related to the immune status of patients, and the detection of immunological indexes may reveal Comprehensive intervention therapy mechanism of action.