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目的探讨茶色素调节血脂紊乱的作用。方法治疗组：２４８例血脂紊乱者；对照组：５５例的血总胆固醇、甘油三酯、高密度脂蛋白胆固醇正常，４１例的血清脂蛋白（ａ）＜３０ｍｇ／ｄｌ，二组均每次口服茶色素１２．５ｍｇ，每日３次。结果治疗一个月后，治疗组血清总胆固醇平均下降１２％（Ｐ＜０．０００１），甘油三脂下降２０％Ｐ＜０．０００１），高密度脂蛋白胆固醇上升２２％（Ｐ＜０．０００１）。对照组总胆固醇与甘油三酯亦明显下降（Ｐ值分别＜０．０１与０．０５），高密度脂蛋白胆固醇与脂蛋白（ａ）无变化，未见明显副作用。结论茶色素为调节血脂紊乱的较好药物，在心＊协作单位：北京阜外心血管医院、北京解放军总医院、北京医科大学第三医院、北京医科大学人民医院、上海市高血压病研究所、江西医学院心血管病研究所、江西医学院二附院心内科、江西萍乡市人民医院脑血管病的防治中可能起重要作用。
Objective To investigate the role of tea pigments in regulating blood lipid disorders. Methods Treatment group: 248 patients with dyslipidemia; control group: 55 cases of total blood cholesterol, triglyceride, high-density lipoprotein cholesterol normal, 41 cases of serum lipoprotein (a) <30mg/dl, both groups each time Oral tea pigment 12.5mg, 3 times a day. Results After one month of treatment, serum total cholesterol decreased by 12% in the treatment group (P<0.0001), triglycerides decreased by 20% (P<0.0001), and high-density lipoprotein cholesterol increased by 22% (P<0.0001). ). The total cholesterol and triglyceride levels in the control group also decreased significantly (P values were <0.01 and 0.05, respectively). There was no change in high-density lipoprotein cholesterol and lipoprotein (a), and no significant side effects were observed. Conclusion tea pigment is a better drug for regulating blood lipid disorders, in the heart * cooperative units: Beijing Fuwai cardiovascular hospital, Beijing General Hospital of PLA, Beijing Medical University Third Hospital, Beijing Medical University People’s Hospital, Shanghai Institute of Hypertension, Institute of Cardiovascular Diseases, Jiangxi Medical College, Department of Cardiology, Second Affiliated Hospital of Jiangxi Medical College, and People’s Hospital of Pingxiang City, Jiangxi, may play an important role in the prevention and treatment of cerebrovascular disease.