广州管圆线虫病是重要的食源性人兽共患寄生虫病,其临床表现多样,可侵犯中枢神经系统、肺部、眼部、乙状结肠等多处脏器。广州管圆线虫入侵宿主造成损伤的机制,认为与多种因素共同作用有关,血脑屏障功能障碍、中枢神经系统功能障碍、免疫反应等均参与其中。了解其发病机制对临床诊断和治疗该病有指导性意义。 Angiostrongylus gonorrhoeae is an important foodborne zoonotic parasitic disease, its clinical manifestations and diversity, can invade the central nervous system, lung, eye, sigmoid colon and other organs. The mechanism of damage caused by C. elegans invaded the host is believed to be related to the interaction of many factors, such as blood-brain barrier dysfunction, central nervous system dysfunction and immune response. To understand the pathogenesis of clinical diagnosis and treatment of the disease has guiding significance.