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目的 观察赛霉安保留灌肠治疗轻、中度溃疡性结肠炎的疗效。方法 对 32例轻、中度末端溃疡性结肠炎病人随机分赛霉安治疗组 (2 0例 )和地塞米松治疗组 (12例 )保留灌肠治疗 1疗程后评估疗效。结果 症状缓解率和内镜缓解率赛霉安治疗组均为 90 % (18/2 0 ) ,地塞米松治疗组为 83 3 % (10 /12 )和 91 7% (11/12 ) ,两组差异无显著性意义(P >0 0 5 )。结论 赛霉安是一种纯中药制剂 ,局部治疗轻、中度溃疡性结肠炎有较好疗效 ,与地塞米松相似 ,且无明显副作用 ,适宜于长期用药
Objective To observe the effect of Sijuanan retention enema in the treatment of mild and moderate ulcerative colitis. Methods 32 patients with mild to moderate terminal ulcerative colitis were randomly divided into two groups: control group (20 cases) and dexamethasone group (12 cases). Results The rate of symptom relief and rate of endoscopic remission were all 90% (18/2) in the treatment group and 83.3% (91/12%) in the dexamethasone group and 91.7% (11/12) in the dexamethasone group There was no significant difference between the two groups (P> 0.05). Conclusion Sedum is a pure Chinese medicine preparation, topical treatment of mild to moderate ulcerative colitis has a good effect, similar to dexamethasone, and no obvious side effects, suitable for long-term medication