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目的探讨冠心病患者同型半胱氨酸(Hcy)水平与性别、年龄相关性。方法将289例住院患者行冠状动脉造影及相关检查后分为冠心病组155例、对照组134例。每组分为中年组与老年组,测血Hcy水平与冠状动脉病变支数、冠心病组的中、老年间性别、年龄与对照组间相关性研究。结果冠心病组的血Hcy水平高于对照组。冠心病组男性血Hcy高于女性;老年组高于中年组,差异均有统计学意义(P<0.05),随冠状动脉病变支数的增加血Hcy水平增高。结论冠心病男女患者血Hcy水平差异有统计学意义,随年龄增长Hcy水平而增加。
Objective To investigate the correlation between homocysteine (Hcy) levels and sex and age in patients with coronary heart disease. Methods 289 hospitalized patients underwent coronary angiography and related tests were divided into coronary heart disease group of 155 cases, control group of 134 cases. Each group was divided into the middle-aged group and the elderly group, blood Hcy levels and coronary lesions, coronary heart disease group, sex, age and control group correlation study. Results The Hcy level in CHD group was higher than that in control group. Hcy in male patients with coronary heart disease was higher than that in female patients. The elderly patients were higher than those in middle-aged patients (P <0.05). Hcy levels increased with the number of coronary lesions. Conclusion There is a significant difference in Hcy levels between male and female patients with coronary heart disease, with the increase of Hcy level with age.