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目的观察垂体后叶素、米索前列醇联合缩宫素用于产后出血的临床治疗效果。方法选取2013年6月-2014年12月医院妇产科收治的产后出血产妇92例,根据产妇病情分为观察组47例和对照组45例,对照组采用常规基础治疗,缩宫素静脉滴注或肌内注射治疗;观察组采用垂体后叶素、米索前列醇联合缩宫素方法治疗。治疗后比较2组产妇子宫收缩情况,阴道出血及不良反应情况。结果 2组治疗后,产后2h、24h出血量均较治疗前明显下降(P<0.05),且观察组低于对照组(P<0.01)。观察组总有效率为93.62%明显高于对照组的73.33%,差异均有统计学意义(P<0.05)。结论垂体后叶素、米索前列醇联合缩宫素治疗产妇产后出血效果明显,出血量明显降低,子宫收缩良好,有相对安全性,降低了孕产妇病死率,值得临床推广应用。
Objective To observe the clinical effect of pituitrin and misoprostol in combination with oxytocin for postpartum hemorrhage. Methods 92 cases of postpartum hemorrhage maternal obstetrics and gynecology admitted from June 2013 to December 2014 in our hospital were divided into observation group (n = 47) and control group (n = 45) according to the maternal condition. The control group was treated with routine basic treatment and oxytocin intravenous infusion Note or intramuscular injection treatment; observation group using pituitrin, misoprostol combined with oxytocin treatment. After treatment, 2 groups of maternal uterine contractions, vaginal bleeding and adverse reactions were compared. Results After treatment, the amount of hemorrhage 2 h and 24 h postpartum were significantly decreased (P <0.05), and the observation group was lower than the control group (P <0.01). The total effective rate in the observation group was 93.62%, which was significantly higher than that in the control group (73.33%), the difference was statistically significant (P <0.05). Conclusions Pituitrin and misoprostol combined with oxytocin are effective in treating postpartum hemorrhage. Hemorrhage was significantly reduced, uterine contractions were good, and relative safety was achieved. Maternal mortality was reduced, which deserved clinical application.