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β—肾上腺素能受体阻滞剂(即β—受体阻滞剂)应用于临床已有十多年历史,是内科治疗心血管系统疾患的常用药。近年来,这类药物在眼科领域里,被应用于青光眼的治疗,虽说机理尚不十分清楚,但它降低眼内压的效果已被肯定。一、肾上腺素能受体在各种组织器官内的作用肾上腺素能受体分为两类。一类为α—受体;一类为β—受体。α—受体兴奋时表现为皮肤、粘膜血管的平滑肌、消化道的括约肌和虹膜瞳孔开大肌收缩,其兴奋物质为去甲肾上腺素即α—受体兴奋剂。酚妥拉明可阻滞α—受体对去甲肾上
Beta-adrenergic receptor blockers (ie, beta-blockers) have been used clinically for more than 10 years and are commonly used medications in the treatment of cardiovascular diseases. In recent years, these drugs in the field of ophthalmology, is used in the treatment of glaucoma, although the mechanism is not yet clear, but it reduces the effect of intraocular pressure has been affirmed. First, the role of adrenergic receptors in various tissues and organs Adrenergic receptors fall into two categories. One is alpha-receptor; one is beta-receptor. When α-receptor is expressed as excited skin, mucosal vascular smooth muscle, gastrointestinal sphincter and iris pupil open great contraction, the excitatory substance is norepinephrine that α-receptor agonist. Phentolamine can block the alpha-receptor on noradrenal