Excellent catalysts with low-temperature activity and relatively wide temperature window for selective catalytic reduction of NO with ammonia (NH3-SCR) are highly demanded in view of the practical treatment of NO.Herein,we have designed a highly active VOx-MnOx/CeO2 material based on the intrinsic requirement of SCR reaction for catalyst,namely redox sites and surface acid sites.The vana-dium oxide and manganese oxide are highly dispersed over the ceria mesosphere via simple incipient wetness impregnation.The loading of manganese could introduce acid sites and enhance the redox property remarkably,while the loading of vanadium increases acid sites and weakens redox property.Through tentatively controlling the appropriate loading ratio of the two components,the optimal catalyst achieves a balance between redox property and surface acidity.The work shed light on the development of new SCR catalyst with superior low temperature activity,wide work temperature window and good hydrothermal stability.