论文部分内容阅读
正常妊娠被认为是一种成功的半同种移植,有赖于母胎界面生理性抑制反应的增强,称为免疫耐受。孕妇的免疫系统失调可以导致生殖失败,同种免疫的异常很有可能是复发性流产的发病机理。随着对免疫耐受机制研究的不断深入,母胎免疫耐受的研究从Th1/Th2细胞平衡失调进一步发展到对Treg/Th17细胞平衡失调的研究,该文综述了Treg/Th17细胞平衡失调在原因不明复发性流产中的作用。
Normal pregnancy is considered a successful semi-allograft, which depends on the physiological inhibition of maternal-fetal interface enhancement, called immune tolerance. Maternal immune system disorders can lead to reproductive failure, alloimmune immune abnormalities is likely to be the pathogenesis of recurrent spontaneous abortion. With the further research on the mechanism of immune tolerance, the research on immune tolerance of maternal fetuses further develops from the imbalance of Th1 / Th2 cells to the study of balance disorders of Treg / Th17 cells. This article reviews the relationship between imbalance of Treg / Th17 cells and the reasons The role of unknown recurrent miscarriage.