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目的探讨颈动脉粥样硬化斑块的稳定性与纤维蛋白原的关系。方法对脑梗死患者应用颈部彩色多普勒超声检测颈部血管斑块形成情况,并同期检测患者血浆纤维蛋白原浓度。结果有斑块组患者纤维蛋白原水平高于无斑块组,不稳定斑块组高于稳定斑块组(P<0.05);随着纤维蛋白原水平增高,不稳定斑块的发生率也随之增高(P<0.01)。结论血浆纤维蛋白原水平和颈动脉粥样硬化斑块的发生及其稳定性有着密切联系。
Objective To investigate the relationship between the stability of carotid atherosclerotic plaques and fibrinogen. Methods Cervical color Doppler ultrasound was used to detect the formation of cervical blood vessel plaque in patients with cerebral infarction. Plasma fibrinogen concentration was measured in the same period. Results The level of fibrinogen in plaque group was higher than that in non-plaque group and the unstable plaque group was higher than that in stable plaque group (P <0.05). With the increase of fibrinogen level, the incidence of unstable plaque With the increase (P <0.01). Conclusions Plasma fibrinogen levels are closely related to the occurrence and stability of carotid atherosclerotic plaques.