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选择我院2009年1月~2010年1月收治的功能性消化不良患者80例,随机分为治疗组和对照组各40例。对照组给予阿米替林治疗,治疗组在此基础上加用吗丁啉治疗。治疗结束后进行临床疗效评定。结果治疗组显效21例,有效16例,总有效率为92.5%;对照组显效10例,有效17例,总有效率为67.5%,两组比较总有效率具有显著性差异(P<0.05);治疗组每周症状改善率均优于对照组,且差异有统计学意义(P<0.05);治疗组药物不良反应发生率5.0%;对照组药物不良反应发生率7.5%,两组相比无显著性差异(P>0.05)。
Eighty patients with functional dyspepsia admitted to our hospital from January 2009 to January 2010 were randomly divided into treatment group (n = 40) and control group (n = 40). The control group was treated with amitriptyline, and the treatment group was treated with domperidone on the basis of this. After the end of treatment for clinical efficacy evaluation. Results In the treatment group, 21 cases were markedly effective and 16 cases were effective. The total effective rate was 92.5%. In the control group, 10 cases were markedly effective and 17 cases were effective. The total effective rate was 67.5%. There was significant difference between the two groups in total effective rate (P <0.05) ; Treatment group weekly symptom improvement rate was better than the control group, and the difference was statistically significant (P <0.05); the incidence of adverse drug reactions in the treatment group was 5.0%; the incidence of adverse drug reactions in the control group 7.5% No significant difference (P> 0.05).