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目的探讨妊娠期高血压疾病妇女和正常妊娠妇女在中孕及晚孕期间血脂指标的关系。方法选取87例妊娠期高血压疾病妇女和127例正常妊娠妇女,分析两组妇女孕中期和孕晚期血总胆固醇(CHOL)、甘油三酯(TG)的变化。结果与正常妊娠组比较,孕中期妊娠期高血压疾病组CHOL无明显变化,两组差异无统计学意义(P>0.05);而孕晚期时妊娠期高血压疾病组CHOL为(6.40±1.41)mmol/L明显高于正常妊娠组的(6.00±1.19)mmol/L,两组差异有统计学意义(P<0.05)。妊娠期高血压疾病组孕中期和孕晚期时TG为(2.38±0.94)和(3.47±1.46)mmol/L显著高于正常妊娠组的(1.77±0.84)和(2.17±0.99)mmol/L,差异均有统计学意义(P<0.01)。结论妊娠期高血压疾病妇女孕晚期血脂明显升高,孕中期时TG变化较CHOL明显,推测对于TG的监测有利于早期预测妊娠期高血压疾病的发生。
Objective To investigate the relationship between serum lipids in pregnant women and normal pregnant women during pregnancy and late pregnancy. Methods Eighty-seven women with gestational hypertension and 127 normal pregnant women were enrolled in this study. The levels of total cholesterol (CHOL) and triglyceride (TG) in the second and third trimester of pregnant women were analyzed. Results Compared with normal pregnancy group, there was no significant difference in CHOL between the third trimester and the third trimester of pregnancy-induced hypertension group (P> 0.05), while CHOL in gestational hypertension group was (6.40 ± 1.41) mmol / L was significantly higher than that of the normal pregnancy group (6.00 ± 1.19) mmol / L, the difference was statistically significant (P <0.05). The levels of TG in gestational hypertension group were (2.38 ± 0.94) and (3.47 ± 1.46) mmol / L in the second trimester and third trimester respectively, significantly higher than those in the normal pregnancy group (1.77 ± 0.84 and 2.17 ± 0.99 mmol / L, The differences were statistically significant (P <0.01). Conclusion The serum levels of lipids in pregnant women with gestational hypertension are significantly increased in the second trimester of pregnancy. The changes of TG in the second trimester are more obvious than those in CHOL. It is speculated that the monitoring of TG is beneficial to predict the occurrence of hypertensive disorders in pregnancy in the early stage.