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研究短串联重复vWⅢ基因应扩增片段长度多态性及其法医学意义。应用STR－PCR分型法对200名中国辽宁汉族无关个体的短串联重复VWFⅢ的多态性进行调查。共检出8个等位基因，频率分布在0．003～0．333，基因长度范围为154～182bP，个人识别能力为0．921，非父排除率为0．581。群体调查证实该基因座符合Hardy－Weinberg平衡，家系调查结果表明其遗传符合孟德尔方式。该基因座可作为人类群体遗传学的一个有价值的多态性标记，可用于法医学个人识别及亲子鉴定。
To study the fragment length polymorphism of short tandem repeat vW Ⅲ gene and its forensic significance. STR-PCR typing was used to investigate the polymorphism of short tandem repeats (VWFⅢ) in 200 unrelated Chinese Han individuals of Liaoning province. A total of 8 alleles were detected with a frequency distribution of 0.003-0.333, a gene length range of 154-182 bp, a personal identification ability of 0.921, and a non-parent exclusion rate of 0.581. Population surveys confirmed that the locus was in line with the Hardy-Weinberg equilibrium, and the pedigree investigation showed that it was inherited in a Mendelian fashion. This locus can be used as a valuable marker of polymorphism in human population genetics and can be used for forensic personal identification and paternity testing.