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实验观察了脉冲噪声长持续时间引起的听觉损伤与短时间引起的听觉损伤是否有明显区别，为修订有关卫生标准和听力保护提供依据。声暴露豚鼠分为５组，接受由同一声源产生的、峰值声压级为１６０ｄＢ、脉冲发数１０发、持续时间分别为５０ｍｓ、１００ｍｓ、２００ｍｓ、４００ｍｓ、和８００ｍｓ的脉冲噪声暴露，并与对照组比较，观察听觉损伤程度的差别。结果表明，暴露后７ｈ起各组听力均开始恢复，但到１４ｄ仍遗留有听力损失。听力损失随着持续时间的增加而加重，组间差异显著。耳蜗毛细胞的缺失以第２、３圈为甚，缺失率和缺失范围也随持续时间的增加而增大。建议修订有关脉冲噪声安全标准时应考虑１００ｍｓ以上时间的作用。
The experiment observes whether there is a significant difference between the auditory damage caused by the long duration of impulse noise and the hearing damage caused by the short time, and provides the basis for revising relevant health standards and hearing protection. The guinea pigs exposed to sound were divided into 5 groups and exposed to impulse noise of 50 ms, 100 ms, 200 ms, 400 ms, and 800 ms generated by the same sound source with a peak SPL of 160 dB and a pulse number of 10, Comparison of the control group, to observe the difference between the degree of auditory impairment. The results showed that the hearing of all groups began to recover at 7h after exposure, but hearing loss still remained after 14 days. Hearing loss increased with the increase of duration, significant difference between groups. Cochlear hair cell loss in the second and third ring is even more, the deletion rate and the deletion range also increases with the increase of duration. Proposed to amend the impulse noise safety standards should consider the role of more than 100ms time.