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实验以组织化学方法和电镜观察研究棉酚对心肌的影响。同时测定动物口服棉酚后,在清醒和麻醉条件下血压、心电图、心收缩力的变化。 将体重165～200g的雄性大鼠分为实验与对照二组。实验组(1)动物经口给棉酚(吐温80悬浮液)30mg/kg,实验组(2)经口给棉酚(吐温80悬浮液)15mg/kg;对照细胞同样剂量吐温80水溶液,各组每
The effects of gossypol on myocardium were studied by histochemistry and electron microscopy. Simultaneous determination of oral gossypol in animals, under awake and anesthesia conditions blood pressure, ECG, cardiac contractility changes. Male rats weighing 165-200 g were divided into experimental and control groups. The experimental group (1) animals were orally gossypol (Tween 80 suspension) 30mg / kg, experimental group (2) gossypol (Tween 80 suspension) 15mg / kg; control cells the same dose of Tween 80 Aqueous solution, each group