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目的探讨经尿道前列腺切除术(TURP)联合去势治疗伴膀胱出口梗阻(BOO)的晚期前列腺癌的临床疗效。方法回顾性分析2003-12-2008-12吉林油田总医院采用经尿道前列腺切除术与双侧睾丸切除术及内分泌治疗18例晚期前列腺癌患者的临床资料。结果经尿道前列腺切除手术时间30～110(平均70)min,切除前列腺重量20～65(平均30)g,出血量40～180(平均90)ml,均未输血;随访2～5 a,2 a内死亡1例,5 a内死亡3例,8例生存至今,失访6例。结论对于全身情况较差、伴有膀胱出口梗阻的晚期前列腺癌患者,经尿道前列腺切除术联合去势治疗是安全有效的方法之一。
Objective To investigate the clinical efficacy of transurethral resection of the prostate (TURP) combined with castration in the treatment of advanced prostate cancer with bladder outlet obstruction (BOO). Methods The clinical data of 18 cases of advanced prostate cancer treated by transurethral resection of prostate and bilateral orchiectomy and endocrine in General Hospital of Jilin Oil Field from December 2003 to December 2008 were retrospectively analyzed. Results The transurethral resection of the prostate was performed in 30 to 110 (average 70) min and 20 to 65 (mean 30) g and 40 to 180 (mean 90) 1 died in a, 3 died in 5 a, 8 survived so far, and lost in 6 cases. Conclusions Transurethral resection combined with castration is a safe and effective method for patients with advanced prostate cancer who have poor systemic conditions and bladder outlet obstruction.