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文章基于原始文献史料考察了《科学通报》1977年首次公开青蒿素化学结构和《光明日报》1978年率先披露青蒿素抗疟功效及其研发过程的经纬,揭示了屠呦呦以及中医研究院中药研究所对发现青蒿素物质和测定青蒿素结构所作出的贡献。作者认为青蒿抗疟研究信息的公开不仅没有对青蒿素发明专利的申请产生负面影响,而且还对屠呦呦2015年获得诺贝尔生理或医学奖起到了一定的促进作用。
Based on the historical data of the original literature, this paper examines the first publication of the chemical structure of artemisinin by the Bulletin of Science Bulletin and the first publication of the artemisinin antimalarial efficacy and its research and development process in 1978 by the Guangming Daily in 1978, revealing that Tu Yo Yo and the Chinese Academy of Medical Sciences Institute of Chinese medicine for the discovery of artemisinin substances and determination of artemisinin structure made by the contribution. The author believes that the publication of Artemisia annua antimalarial research information not only did not have a negative impact on the application of artemisinin patents, but also played a certain role in promoting Tu Yo Yo Nobel Prize in Physiology or Medicine in 2015.