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目的探讨肺癌伴嗜酸性粒细胞增多性胸腔积液(EPE)的特点,以期为临床决策提供一定参考。方法以胸腔积液中嗜酸性粒细胞是否增多为标准,对312例经纤维支气管镜、痰液脱落细胞学、肺CT确诊肺癌患者进行分组。结果肺癌伴嗜酸性粒细胞增多与不伴嗜酸性粒细胞增多性胸腔积液的淋巴细胞数、Rivalta试验、乳酸脱氢酶(LDH)、癌胚抗原(CEA)均有差异(P<0.05)。结论胸腔积液中嗜酸性细胞增多不要忽视恶性肿瘤的可能。
Objective To investigate the characteristics of lung cancer with eosinophilic pleural effusion (EPE) in order to provide a reference for clinical decision-making. Methods According to whether pleural effusion eosinophilia increased, 312 cases of lung cancer diagnosed by bronchofibroscopy, sputum exfoliative cytology and lung CT were divided into groups. Results There was a significant difference in Rivalta test, lactate dehydrogenase (LDH) and carcinoembryonic antigen (CEA) between lung cancer with eosinophilia and lymphocytosis without eosinophilic pleural effusion (P <0.05) . Conclusion Pleural effusion eosinophilia do not ignore the possibility of malignant tumors.