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通过对肾移植术后早期大量腹水 1例患者的治疗回顾及文献复习 ,提示环孢 A(CSA)可引起大量白蛋白由血管内皮渗出造成低蛋白血症 ,不仅导致腹水、组织水肿 ,更值得注意的是由于低蛋白血症所致有效血容量降低 ,肾血流减少、肾脏低灌注及滤过率降低 ,从而造成对移植肾功能的继发性影响 ,因此应在今后临床工作中引起重视。
A retrospective review of the treatment of a large number of patients with ascites after renal transplantation and review of the literature suggest that cyclosporin A (CSA) can cause a large number of albumin exudation caused by vascular endothelial hypoproteinemia, not only cause ascites, tissue edema, more It is noteworthy that due to hypoalbuminemia due to reduced blood volume, decreased renal blood flow, renal hypoperfusion and decreased filtration rate, resulting in secondary effects on renal graft function, it should be caused in future clinical work Pay attention.