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黏膜免疫系统(MIS)是独立于免疫系统之外的一种复杂的免疫系统,包含机体80%的免疫细胞和50%以上的淋巴组织,是机体抵抗外来病原微生物的第一道防线。黏膜免疫系统包括胃肠道黏膜、呼吸道黏膜、泌尿生殖道黏膜、一些外分泌腺黏膜、黏膜固有层与上皮细胞下分散的无被膜淋巴细胞、一些有生发中心器官化淋巴组织等,由特异性和非特异性黏膜免疫组成,是局部特异性免疫的主要场所,也是机体免疫系统的重要组成部分。文章就消化道、呼吸道黏膜免疫系统结构与功能的研究进行综述。
Mucosal immune system (MIS) is a complex immune system independent of the immune system, including 80% of the body’s immune cells and more than 50% of lymphoid tissues, the body’s first line of defense against foreign pathogens. Mucosal immune system, including gastrointestinal mucosa, respiratory mucosa, genitourinary tract mucosa, some exocrine mucosa, mucosal lamina propria and epithelial cells scattered non-membranous lymphocytes, some have germinal center organ lymphoid tissue by the specificity and Non-specific mucosal immune components, is the main site of local specific immunity, but also an important part of the body’s immune system. The article reviews the structure and function of the digestive tract and respiratory mucosal immune system.