自1975年起,意大利Leptit研究所Lerner、Galliani等开始研究一类人工合成的非甾体、非前列腺素抗早孕药——二苯三唑类及其有关的类似物,并在多种哺乳类包括灵长目动物作了大量的实验研究。迄今所得资料表明,这类药物抗早孕作用较强,副作用较小,有可能发展成为具有临床价值的抗早孕药。本文试对这类药物的研究状况作一综述。一、概况(一)历史回顾 Since 1975, Leptit Institute of Italy Lerner, Galliani, etc. began to study a class of synthetic non-steroidal, non-prostaglandin anti-early pregnancy drug - diphenyltriazole and its related analogues, and a variety of mammals Including primate animals made a lot of experimental research. The data so far show that these drugs have a strong anti-early pregnancy effect, less side effects, may develop into a clinical value of anti-early pregnancy drugs. This article tries to review the research status of these drugs. First, an overview (a) historical review