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目的:探讨小儿传染性单核细胞增多症(IM)的诊断及治疗过程。方法:对52例小儿染性单核细胞增多症的临床诊疗过程进行回顾性分析。结果:1~6岁的儿童发病率较高,占81.8%;临床症状无特异性,可以有多种表现,有的仅表现发热、眼睑浮肿、皮疹,部分除含淋巴组织的肝、脾、浅表淋巴结肿大、咽峡炎外,其他多器官也可受累,多数患者多脏器损害。结论:对淋巴结、发热、肝、脾无明原因肿大且淋巴细胞比例明显升高者,需行白细胞分类,特别是异型淋巴细胞检测,血清EBIg M检测,早诊断,早治疗是提高临床治愈率的关键;肝功能受累及血液系统改变是最常见的并发症,严重者可导致EB病毒感染相关噬血细胞综合征预后差,病情凶险,应加强监测。
Objective: To investigate the diagnosis and treatment of childhood infectious mononucleosis (IM). Methods: The clinical diagnosis and treatment of 52 cases of pediatric infectious mononucleosis were retrospectively analyzed. Results: The incidence of children aged 1 ~ 6 years old was high, accounting for 81.8%. The clinical symptoms were nonspecific and could have many manifestations. Some of them showed fever, eyelid edema and skin rashes, Superficial lymph nodes, angina, the other multiple organs can also be involved, most of the patients with multiple organ damage. Conclusion: Lymph nodes, fever, liver and spleen no cause of swelling and a significant increase in the proportion of lymphocytes, the need for white blood cell classification, especially atypical lymphocytes, serum EBIg M detection, early diagnosis and early treatment is to improve clinical cure Rate of the key; liver involvement and blood system changes are the most common complication, severe cases can lead to Epstein-Barr virus infection-related hemophagocytic syndrome prognosis is poor, dangerous, should be strengthened monitoring.