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通常甲型肝炎呈急性、自限性经过,且无长期带毒状态,但近年来不断有甲型肝炎慢性化的报告。作者报告1例男性2(?)岁患者,1983年11月第一次发生黄疸型肝炎,IgM抗-HAV阳性。1984年4月复发,IgM抗-HAV仍阳性。复发过程中服用强的松龙45mg/天,共2周。1984年7月再次复发。肝活检示门管区慢性炎细胞浸润及碎屑样坏死,诊断为慢性肝炎。以后连续3年每年肝活检1次,均提示架桥性坏死、淋巴细胞浸润和进行性纤维化。1987年12月最后一次组织学认为发
Hepatitis A is usually acute, self-limiting, and no long-term poisoning status, but in recent years there have been reports of chronic hepatitis A. The authors report 1 male 2 (?) Years of age, the first occurrence of jaundice hepatitis in November 1983, IgM anti-HAV positive. Recurrence in April 1984, IgM anti-HAV is still positive. The course of relapse took prednisolone 45mg / day, a total of 2 weeks. July 1984 relapse again. Liver biopsy showed chronic inflammatory cell infiltration and debris-like necrosis, diagnosis of chronic hepatitis. Three consecutive years after the annual liver biopsy 1, were prompted bridging necrosis, lymphocytic infiltration and progressive fibrosis. In December 1987 the last histological think hair