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目的:评价间苯三酚在妊娠期肾绞痛中的应用。方法:将21例妊娠期结石性肾绞痛患者随机分成两组,治疗组静脉滴注间苯三酚,对照组静脉滴注山莨菪碱。同时联合硫酸镁,黄体酮治疗。观察组间止痛效果,复发率及不良反应。结果:止痛效果:治疗组(间苯三酚)总有效率为90.90%,对照组(山莨菪碱)为70.00%;复发率:前者18.18%,后者50.00%。组间比较止痛总有效率及复发率差异均有统计学意义(P<0.05)。治疗组(间苯三酚)未见不良反应。2例肾绞痛频繁发作者予输尿管镜下弹道碎石术渐缓解。结论:相比山莨菪碱,静脉应用间苯三酚治疗妊娠期肾绞痛镇痛效果肯定、能有效安胎且无明显不良反应。
Objective: To evaluate the application of phloroglucinol in gestation renal colic. Methods: Twenty-one patients with lithogenic renal colic during pregnancy were randomly divided into two groups. The treatment group received intravenous phloroglucinol and the control group received anisodamine. At the same time combined magnesium sulfate, progesterone treatment. The analgesic effect, recurrence rate and adverse reactions in the observation group were observed. Results: Analgesic effect: The total effective rate was 90.90% in the treatment group (phloroglucinol) and 70.00% in the control group (Anisodamine). The recurrence rate was 18.18% in the former and 50.00% in the latter. There was significant difference between the two groups in the total effective rate of analgesia and the recurrence rate (P <0.05). Treatment group (phloroglucinol) no adverse reactions. 2 cases of frequent occurrence of renal colic ureteroscopic lithotripsy gradually relieve. Conclusion: Compared with anisodamine, intravenous phloroglucinol treatment of renal colic in pregnancy analgesic effect is affirmative, effective tocolysis without significant adverse reactions.