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豆科野百合属植物共有300种以上,印度约产70种。本属植物由于含双稠吡咯啶生物碱而为众所周知,有认为双稠吡咯啶羧酸酯的毒性是由于结构中的烯丙基所致,但少数饱和双稠吡咯啶生物碱是无毒的。例如Platyphylline(Ⅰ)在苏联用作镇痉药,半合成的双稠吡咯啶羧酸Diplacine(Ⅱ)用作筒箭毒碱氯化物的代用品。此外,野百合碱(Monocrotaline)、Integerimine和Usaramine均具显著的降压作用;合成的Trachelanthamidine的对氨基苯甲酸酯衍生物具有与可
There are more than 300 Leguminous Lilium species and about 70 species in India. It is well-known that this genus contains dipyrrhizin alkaloids, which are believed to be due to the allyl groups in the structure, but the few saturated di-pyrrolizidine alkaloids are non-toxic . For example, Platyphylline (I) is used as antispitaxis in the Soviet Union, and semipyclidine diplacine (II) is used as a surrogate for myostatin chloride. In addition, monoclotaline (Monocrotaline), Integerimine and Usaramine have significant antihypertensive effect; synthetic Trachelanthamidine p-aminobenzoate derivatives with the available