论文部分内容阅读
目的探讨腹腔镜切除病灶联合曼月乐对子宫腺肌症的治疗效果及对卵巢功能的影响。方法选择2012年4月-2015年5月该院收治的子宫腺肌症患者98例作为研究对象,采用随机数字表法分为观察组和对照组,每组各49例。观察组患者采用腹腔镜切除病灶联合曼月乐治疗,对照组患者采用腹腔镜切除病灶联合米非司酮治疗。对比分析两组患者治疗前后的月经情况及卵巢功能,观察两组患者的治疗效果及不良反应。结果对照组患者的总有效率(75.51%)明显低于观察组(91.84%),组间比较差异有统计学意义(P<0.05);治疗前,两组患者月经情况比较差异无统计学意义(P>0.05),治疗后,两组患者月经期及痛经程度评分较治疗前明显减少(P<0.05),治疗后两组患者的月经期及月经周期组间比较差异无统计学意义(P>0.05);治疗后观察组患者的痛经程度评分明显低于对照组患者(P<0.05)。治疗前,两组患者LH、FSH、LH/FSH、E_2指标水平比较差异无统计学意义(P>0.05);治疗后,两组患者的LH、FSH、LH/FSH、E_2指标水平较治疗前显著降低(P<0.05),且观察组的LH、FSH、LH/FSH、E_2指标水平显著低于对照组(P<0.05)。两组患者不良反应均较轻,组间比较差异无统计学意义(P>0.05)。结论:子宫腺肌症患者行腹腔镜下囊肿剔除术后使用曼月乐进行辅助治疗,疗效确切,且对患者的月经情况及卵巢功能有着明显的改善作用,安全性好,应在临床上进行推广使用。
Objective To investigate the therapeutic effect of laparoscopic resection combined with Mirena on adenomyosis and its effect on ovarian function. Methods From April 2012 to May 2015, 98 cases of patients with adenomyosis admitted to our hospital were selected as study subjects, and divided into observation group and control group by random number table, with 49 cases in each group. Patients in the observation group were treated with laparoscopic resection of Mirena, and patients in the control group were treated with laparoscopic removal of mifepristone. The two groups were compared before and after treatment of menstrual conditions and ovarian function, observation of the two groups of patients with treatment and adverse reactions. Results The total effective rate (75.51%) in the control group was significantly lower than that in the observation group (91.84%), with significant difference between the two groups (P <0.05). Before treatment, there was no significant difference in menstruation between the two groups (P> 0.05). After treatment, the scores of menstrual period and dysmenorrhea in both groups were significantly lower than those before treatment (P <0.05), and there was no significant difference between the two groups in the menstrual period and menstrual cycle after treatment (P > 0.05). After treatment, the degree of dysmenorrhea in the observation group was significantly lower than that in the control group (P <0.05). Before treatment, the levels of LH, FSH, LH / FSH and E_2 had no significant difference between the two groups (P> 0.05). After treatment, the levels of LH, FSH, LH / FSH and E_2 in both groups were significantly higher than those before treatment (P <0.05), and the levels of LH, FSH, LH / FSH and E 2 in the observation group were significantly lower than those in the control group (P <0.05). Adverse reactions were mild in both groups, with no significant difference between the two groups (P> 0.05). Conclusions: The patients with adenomyosis underwent laparoscopic cyst excision with Mirena adjuvant therapy, the curative effect is exact, and the patient’s menstrual conditions and ovarian function has a significant improvement, safety should be carried out clinically Promote use.