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雷公藤春碱(wilfortrine)和雷公藤新碱(euonine)ip 40及80 mg/kg对以溶血素反应为指标的体液免疫具有明显的抑制作。用雷公藤春碱ip 160mg/kg对GVHR为指标的细胞免疫也具有抑制作用。雷公藤新碱对DNCB所引起迟发超敏反应具有显著的抑制作用,并且能够降低小鼠碳廓清率和脾脏、胸腺的重量。
The wilfortrine and eupineine ip 40 and 80 mg/kg had significant inhibitory effects on humoral immunity using the hemolysin response as an indicator. The use of Tripterygium ipiolide ip 160 mg/kg also had an inhibitory effect on cellular immunity against GVHR. Tripterygline has a significant inhibitory effect on late-onset hypersensitivity caused by DNCB, and it can reduce the carbon clearance rate of mice and the weight of spleen and thymus.