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目的探究钬激光前列腺剜除术(HoLEP)与经尿道前列腺电切术(TURP)治疗前列腺良性增生临床效果。方法 64例前列腺良性增生患者,随机分为HoLEP组和TURP组,各32例。HoLEP组采用HoLEP治疗,TURP组采用TURP治疗,观察对比两组术前、术后各项最大尿流率(Qmax)、国际前列腺症状评分(IPSS)、生活质量(QOL)评分及并发症发生率。结果术后两组IPSS评分、QOL评分、Qmax较术前显著改善,差异有统计学意义(P<0.05),但组间比较差异无统计学意义(P>0.05);术后HoLEP组低血钠发生率为6.25%(2/32),低于TURP组的31.25%(10/32),差异有统计学意义(P<0.05),两组尿失禁发生率对比差异无统计学意义(P>0.05)。结论 HoLEP与TURP治疗前列腺良性增生均具有良好疗效,相较于TURP,HoLEP可明显降低前列腺良性增生患者低血钠发生率,改善预后。
Objective To investigate the clinical effects of holmium laser prostatectomy (HoLEP) and transurethral resection of prostate (TURP) on benign prostatic hyperplasia. Methods 64 patients with benign prostatic hyperplasia were randomly divided into HoLEP group and TURP group, 32 cases in each. HoLEP group was treated with HoLEP and TURP group was treated with TURP. The preoperative and postoperative maximum flow rate (Qmax), International Prostate Symptom Score (IPSS), quality of life (QOL) score and complication rate were compared between the two groups . Results The postoperative IPSS score, QOL score and Qmax were significantly improved compared with that before operation (P <0.05), but there was no significant difference between the two groups (P> 0.05) The incidence of sodium was 6.25% (2/32), which was lower than that of TURP group (31.25%, 10/32) (P <0.05). There was no significant difference in the incidence of urinary incontinence between the two groups (P > 0.05). Conclusions HoLEP and TURP are effective in treating benign prostatic hyperplasia. Compared with TURP, HoLEP can significantly reduce the incidence of hyponatremia and improve the prognosis of patients with benign prostatic hyperplasia.