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目的了解Castleman病(Castleman’s Disease,CD)的临床特征并提高诊断和治疗水平。方法报道1例以嗜酸细胞升高为主要表现的CD的临床资料并结合文献复习,为其诊断和鉴别诊断提供新思路。结果患者男性,57岁,体检发现嗜酸细胞增多;双侧颈部、腋窝、腹股沟及腹膜后多个淋巴结肿大;淋巴结活检病理:血管滤泡性淋巴结组织增生,浆细胞型。结论临床表现多样,组织病理学检查或淋巴结活检有益于早期诊断,最佳治疗效果基于组织病理学和临床分类。
Objective To understand the clinical features of Castleman’s disease (CD) and improve the diagnosis and treatment. Methods One case of eosinophils as the main manifestation of CD clinical data and literature review, provide a new idea for the diagnosis and differential diagnosis. Results Male patients, 57 years old, physical examination found eosinophilia; bilateral neck, axillary, groin and multiple retroperitoneal lymph nodes; lymph node biopsy pathology: vascular follicular lymph node tissue proliferation, plasma cell type. Conclusions Various clinical manifestations, histopathological examination or lymph node biopsy beneficial early diagnosis, the best treatment based on histopathological and clinical classification.