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为了探讨肺腺癌细胞系中金属蛋白酶的活性与其转移能力之间的相关性 ,选取9个转移能力不同的肺腺癌细胞系 ,分别对它们所分泌的金属蛋白酶MMP -2、MMP -9进行活性分析。结果发现 ,金属蛋白酶的活性与肺腺癌细胞系的转移能力有一定的相关性 ,其中MMP -9的活性与肺腺癌细胞系的转移相关性更显著。
To investigate the correlation between the activity of metalloproteinases and their metastatic potential in lung adenocarcinoma cell lines, nine lung adenocarcinoma cell lines with different metastatic capacities were selected and their metalloproteinases MMP-2 and MMP-9 were secreted. Activity analysis. The results showed that the activity of metalloproteinases was correlated with the metastatic capacity of lung adenocarcinoma cell lines, and the activity of MMP-9 was more related to the metastasis of lung adenocarcinoma cell lines.