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目的:了解西宁地区女性人乳头瘤病毒(HPV)感染基因亚型分布及年龄特点。方法:采用凯普医用核酸分子快速导流杂交基因芯片技术(Hybrimax),对8 700名2009年8月—2011年12月在我院就诊的女性进行生殖道21种HPV感染基因亚型筛查。结果:8 700名女性HPV感染率为16.1%,其感染率随年龄增长而呈下降趋势(P<0.05),HPV感染以单一感染为主,占76.4%,多重感染占23.6%。结论:西宁地区女性HPV感染以单一型为主,符合亚洲人群分布规律。
Objective: To understand the distribution and age characteristics of the female subtype of human papillomavirus (HPV) in Xining area. Methods: Hybrimax was used to screen 21 subtypes of HPV genotypes in reproductive tract in 8 700 women who visited our hospital from August 2009 to December 2011 . Results: The HPV infection rate of 8 700 women was 16.1%. The infection rate decreased with age (P <0.05). HPV infection was mainly single infection, accounting for 76.4% and multiple infection was 23.6%. Conclusion: The prevalence of HPV infection in Xining women is mainly of single type, which accords with the distribution of Asian people.