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ST段抬高急性心肌梗死(ST-se AMI)患者心肌损伤与血小板活性之间的关系尚不清楚。台湾学者Yip HK等探讨了行直接冠脉支架植入术的ST-se AMI患者血小板活性(通过 CD62p表达)增加,对预测心肌损伤程度和30天临床预后的可能性。研究结果发表在Circulation Journal杂志上。研究人员对连续入选的45例ST-se AMI患者,于冠脉支架植入前应用流式细胞术检测CD62p表达,同时还检测了20 例健康者及20例具有AMI风险的志愿者CD62p。前者CD62p
The relationship between myocardial damage and platelet activation in patients with ST-se AMI is not clear. Taiwan scholar Yip HK et al investigated the increase of platelet activity (expressed by CD62p) in patients with ST-se AMI undergoing direct coronary stenting for predicting the degree of myocardial damage and the likelihood of a 30-day clinical prognosis. The study was published in the journal Circulation Journal. The researchers selected 45 consecutive patients with ST-se AMI before coronary stent implantation using flow cytometry CD62p expression was detected in 20 healthy subjects and 20 patients with AMI at risk of detection of CD62p. The former CD62p