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马拉硫磷(4049)为一高效低毒的有机磷农药。我国湖北省葛店联合化工厂所产之马拉硫磷已应用于粮谷的保藏,对杀害仓库害虫有较明显的效果,可达到延长粮食储存期的目的。同时国外也有一些国家使用马拉硫磷保藏粮谷。但粮谷为一长期大量食用的食品,如长期食用含有马拉硫磷过多的粮食,可能对人体引起毒害。为了保护人民健康,正确合理使用马拉硫磷,必须确定粮食中含有多少马拉硫磷经长期食用对人体安全无害,并在此基础上制订粮食中马拉硫磷允许残留量标准。本文对国产马拉硫磷进行了急性和亚急性中毒动物试验,并对其肝、脑、血液、血浆、血球进行了胆碱酯酶活力的测定,初步得出马拉硫磷在粮谷中允许含有的比较安全的数量。
Malathion (4049) is a high efficiency and low toxicity organophosphorus pesticide. China’s Hubei Province Gedian United Chemical Plant production of malathion has been applied to the storage of grain, to kill the warehouse pests have a more significant effect, can achieve the purpose of extending food storage period. At the same time, some foreign countries also use malathion to preserve grain. However, grain is a food that has been consumed in large quantities for a long time. For example, long-term consumption of food containing too much malathion may cause poisoning to the human body. In order to protect the health of the people and to use malathion correctly and reasonably, it is necessary to determine how much malathion contained in the food is not harmful to the human body after long-term consumption, and on this basis, the allowable residue level of malathion in food should be set. In this paper, acute and sub-acute poisoning of domestic malathion was tested, and the activity of cholinesterase in liver, brain, blood, plasma and blood was measured. The results showed that malathion was allowed to contain The safer amount.