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氟康唑为目前治疗霉菌感染盛用的药物,临床已广泛使用,并取得良好的疗效。现就我院1993年8月～1994年6月间应用氟康唑治疗30例霉菌感染的疗效和毒副作用小结如下。 临床资料 一、一般资料:男性20例,女性10例,年龄15～68岁(中位数59岁)。本组病例原发疾患包括:1.血液系统疾患18例,其中急性白血病9例,恶性淋巴瘤5例,恶性组织细胞病1例,慢性淋巴细胞白血病1例,急性再生障碍性贫血1例,难治性原发性血小板减少性紫癜1例。2.呼吸系统疾患8例,有慢性阻塞性肺疾患4例,肺癌3例,急性支气管炎1例。3.皮肤霉菌感染3例,有体癣2例,甲癣1例,其它1例为中枢性昏迷。
Fluconazole is currently used in the treatment of fungal infections, the clinical has been widely used, and achieved good results. Now on our hospital from August 1993 to June 1994 application of fluconazole treatment of 30 cases of fungal infections and side effects are summarized below. Clinical data First, the general information: 20 males and 10 females, aged 15 to 68 years (median 59 years). The primary disease in this group of patients include: 1. 18 cases of hematological disorders, including acute leukemia in 9 cases, 5 cases of malignant lymphoma, 1 case of malignant histiocytosis, 1 case of chronic lymphocytic leukemia, 1 case of acute aplastic anemia, A case of refractory idiopathic thrombocytopenic purpura. 2. Respiratory disorders in 8 cases, 4 cases of chronic obstructive pulmonary disease, lung cancer in 3 cases, 1 case of acute bronchitis. 3 skin mold infection in 3 cases, there are 2 cases of body ringworm, 1 case of onychomycosis, the other 1 case of central coma.