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自从发现脑内存在阿片受体以及与受体作用的内源性吗啡样物质以来,为针麻原理的深人研究提供了物质基础。第三脑室及导水管周围灰质微量注射吗啡能明显引起镇痛,此作用可以被阿片受体阻断剂naloxone部分阻断,业已证明吗啡镇痛与阿片受体有关。近年来随着针麻原理的进一步揭示,发现针刺促使脑内某些核团释放内源性吗啡样物质,并通过阿片受
Ever since the discovery of opioid receptors in the brain and endogenous morphine-like substances that interact with receptors, this has provided the material basis for further studies on the principle of acupuncture anesthesia. Microinjection of morphine into the gray matter around the third ventricle and the aqueduct can cause marked analgesia. This effect can be partially blocked by naloxone, an opioid receptor blocker, and morphine analgesia has been shown to be associated with opiate receptors. In recent years, with the further revelation of acupuncture anesthesia principle, acupuncture was found to promote some nuclei in brain release endogenous morphine-like substance,