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目的优选参玉口服液最佳提取工艺。方法采用L9(34)正交试验法,以人参总皂苷含量为醇提工艺评价指标,以总多糖含量和总甾体皂苷含量为水提工艺评价指标,分别进行人参醇提和处方水提工艺优化选择,考察各因素的影响。结果人参醇提的最佳工艺为:加8倍量60%乙醇提取3次,每次4h;处方水提最佳工艺为:药材加20倍量水,煎煮提取3次,每次2h。结论优选出的最佳提取工艺稳定可行,为院内制剂参玉口服液的二次开发提供实验依据。
Objective To optimize the best extraction process Shen Yu oral solution. Methods The L9 (34) orthogonal test was used to determine the content of total ginsenosides in alcohol extraction process. Total polysaccharide content and total steroidal saponin content were used as evaluation indexes of water extraction process. Optimize the choice, examine the impact of various factors. Results The best extraction process of ginseng alcohol was: add 8 times the amount of 60% ethanol extracted 3 times, each time 4h; prescription water extraction optimum process: herbs plus 20 times the amount of water, boiling extraction 3 times, each time 2h. Conclusion The optimal extraction process is stable and feasible, which provides an experimental basis for the secondary development of Shenyu oral liquid in the hospital.