华支睾吸虫病是我国重要的寄生虫病之一,在四川省流行范围也很广,患者以农村儿童为多见,大多因食生(烧)鱼而感染。第二中间宿主主要为稻田中的麦穗鱼,其感染率与感染度均较高,每条鱼含囊蚴数常达数百个。因此,患儿常引起营养不良,甚至发育障碍。近年我们在四川省资阳及德阳县观察了不同剂量与疗程的吡喹酮对该病的疗效,取得初步效果。现总结248例的研究结果,并对最佳剂量与疗程进行探讨。 Clonorchis sinensis is one of the most important parasitic diseases in our country. It is also endemic in Sichuan Province. Most of the patients are rural children, most of whom are infected with food-borne fish. The second intermediate host is mainly wheat ears in paddy fields, and its infection rate and infection rate are higher, and the number of metacercariae per fish often reaches several hundreds. Therefore, children often cause malnutrition, and even developmental disorders. In recent years, we observed the effects of different doses and courses of praziquantel on the disease in Ziyang and Deyang counties of Sichuan province, and achieved initial results. 248 cases are summarized the results of the study, and the best dose and treatment to be explored.