染色体异常是引起不孕不育、习惯性流产、死胎、胎儿畸形的重要原因之一,在妊娠早期自发流产大约50%染色体异常所致。男性不育中约占15%-20%由克氏综合征引起的。本资料有不良孕产史夫妇共96例患者进行了细胞遗传学分析,探讨其与染色体异常的关系。资料与方法 Chromosomal abnormalities are one of the important causes of infertility, habitual miscarriage, stillbirth and fetal malformation. About 50% of chromosomal abnormalities occur in spontaneous abortion in early pregnancy. About 15% -20% of male infertility caused by Klinefelter’s syndrome. This information has adverse pregnancy history of a total of 96 patients were cytogenetically analyzed to explore the relationship with chromosomal abnormalities. Materials and Methods