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鳞状细胞癌是肺癌最常见类型。以往实验治疗研究大多采用动物肿瘤模型,研究结果与临床相关性较差。为了建立体外环境下的人癌整体实验体系,从1983年6月起,我们将一例人肺鳞状细胞癌移植于裸小鼠,至今已传到33代。移植瘤生长良好。本文报告对其超微结构进行系统观察的结果。实验用Swiss-DF品系裸小鼠在无特殊病原环境下繁育。鼠令6～12周;体重12～28克,雌雄兼用。移植瘤
Squamous cell carcinoma is the most common type of lung cancer. Most of the previous experimental treatment studies used animal tumor models, and the correlation between clinical and clinical outcomes was poor. In order to establish an overall human cancer experimental system in an in vitro environment, we have transplanted one case of human lung squamous cell carcinoma into nude mice since June 1983 and it has been reported for 33 generations. The transplanted tumor grew well. This article reports the results of a systematic observation of its ultrastructure. The nude mice of the Swiss-DF strain were bred in a special pathogen-free environment. Rats 6 to 12 weeks; weighing 12 to 28 grams, both male and female. Transplantation tumor