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目的 :比较介入化疗 (介化 )联合放疗和单纯介入化疗对中晚期宫颈癌的近期疗效。方法 :随机选择经病理确诊的 19例中晚期宫颈癌 ,采用含 DDP+ CTX为主要化疗药物进行双侧髂内动脉灌注及栓塞髂内动脉后 ,短期内行盆腔内照射 ;另2 6例宫颈癌单纯行介化治疗后不做盆腔内照射。观察两组的近期疗效。结果 :介化联合放疗组的近期有效率达 82 .4% ,肿物平均在 16d内消失 ;单纯介化组的近期有效率为 65.4% ,肿物平均 3 3 d才消失。两组的有效率和症状改善率具有明显的差异 (P<0 .0 5)。结论 :用介入化疗联合放疗可提高宫颈癌的近期疗效
Objective: To compare the short-term effects of interventional chemotherapy (mediation) combined with radiotherapy and simple interventional chemotherapy on advanced cervical cancer. Methods: Totally 19 cases of advanced cervical cancer diagnosed by pathology were randomly selected. The patients were treated with DDP + CTX as the main chemotherapy drug for bilateral internal iliac artery perfusion and embolization of the internal iliac artery, followed by short-term intra-pelvic irradiation. The other 26 cases of cervical carcinoma were simple Line of media after treatment does not do pelvic irradiation. The two groups observed the short-term efficacy. Results: The effective rate of mediating combined radiotherapy group was 82.4%, the tumor disappeared within 16 days on average; the effective rate of the simple mediation group was 65.4%, and the tumor disappeared on the average of 33 days. There was a significant difference between the two groups in the rate of improvement and symptom improvement (P <0.05). Conclusion: Interventional chemotherapy combined with radiotherapy can improve the curative effect of cervical cancer