论文部分内容阅读
目的探讨中西医结合治疗老年重症急性胰腺炎(Elder sever acute pancreatitis,ESAP)的临床疗效。方法回顾性分析我院1997年1月至2007年1月间收治的52例≥60岁SAP患者的临床资料,其中经常规西医治疗(对照组)26例,中西医结合治疗(治疗组)26例。结果治疗组1周APACHEⅡ评分为(8.8±1.9),2周Balthaza CT评分为(3.3±1.2),血淀粉酶降至正常时间(4.6±2.4)d,住院时间(58.2±11.6)d,对照组对应指标为(11.2±2.5),(4.8±1.6),(6.9±1.6)d,(71.6±8.6)d,2组差异有统计学意义Ρ<0.005,P<0.01,P<0.005,P<0.001。治疗组手术干预率7.7%(2/26),严重并发症发生率23.1%(6/26),严重腹胀发生率46.2%(12/26),病死率23.1%(6/26),对照组对应指标30.8%(8/26),61.5%(16/26),76.9%(20/26),50.0%(13/26),2组差异均有统计学意义P<0.05。结论中西医结合治疗ESA P能加快降低血淀粉酶,降低1周APACHEⅡ评分和2周Balthaza CT评分,降低手术干预率,严重并发症发生率及病死率,疗效优于常规西医治疗。
Objective To investigate the clinical efficacy of integrated traditional Chinese and western medicine in the treatment of Elder sever acute pancreatitis (ESAP). Methods The clinical data of 52 patients with SAP≥60 years admitted from January 1997 to January 2007 in our hospital were retrospectively analyzed. Among them, 26 were routine western medicine (control group), 26 were treated by traditional Chinese and Western medicine (treatment group) example. Results The APACHE II score was (8.8 ± 1.9) at 1 week, Balthaza CT score at 2 weeks was (3.3 ± 1.2), blood amylase was decreased to normal time (4.6 ± 2.4) days, and hospital stay was (58.2 ± 11.6) days. (11.2 ± 2.5), (4.8 ± 1.6), (6.9 ± 1.6) d, (71.6 ± 8.6) d respectively, the difference was statistically significant between the two groups (P <0.005, P <0.01, P <0.005, P <0.001. In the treatment group, the intervention rate was 7.7% (2/26), the incidence of serious complications was 23.1% (6/26), the incidence of severe abdominal distension was 46.2% (12/26) and the mortality rate was 23.1% (6/26) The corresponding indexes were 30.8% (8/26), 61.5% (16/26), 76.9% (20/26) and 50.0% (13/26), respectively. The differences between the two groups were statistically significant (P <0.05). Conclusion The combination of traditional Chinese and Western medicine treatment of ESA P can speed up the reduction of serum amylase, APACHE Ⅱ 1 week and 2 weeks Balthaza CT score, reduce the intervention rate of surgery, the incidence of serious complications and mortality, the effect is superior to conventional Western medicine.