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对20例肝门部胆管癌的术前诊断方法进行研究。结果提示：胆汁脱落细胞检查、刷取细胞检查和钳取组织活检的阳性率分别为10％、52．6％和75％。联合应用三种检查方法可使诊断的敏感性提高到84．2％。60％的病人血清CA19－9值显著升高，达正常值的6倍以上。B超、电脑彩超、CT和磁共振胆道成像的确诊率分别为55％、85％、55％和91．4％。肝门部胆管癌的术前诊断可分两步进行。首先，通过B超结合临床资料对病人初步筛选，然后采用三项检查法：（1）血清CA19－9值测定（若＞222kU／L）；（2）电脑彩超；（3）磁共振、磁共振胆道成像或螺旋CT胆道成像。如果两项以上检查结果提示肿瘤征象，则可基本上确诊为肝门部胆管癌。
The preoperative diagnostic method for 20 cases of hilar cholangiocarcinoma was studied. The results suggest that the positive rates of bile exfoliative cell examination, brushing cell examination, and forceps biopsy were 10%, 52.6%, and 75%, respectively. Combined application of the three methods can increase the diagnostic sensitivity to 84.2%. Serum CA19-9 levels were significantly elevated in 60% of patients, more than 6 times the normal value. The definitive diagnosis rates for B ultrasound, computer color ultrasound, CT, and magnetic resonance biliary imaging were 55%, 85%, 55%, and 91.4%, respectively. Preoperative diagnosis of hilar cholangiocarcinoma can be performed in two steps. First, the patients were initially screened by B-ultrasound combined with clinical data, and then three tests were used: (1) Determination of serum CA19-9 (if >222 kU/L); (2) Computer color Doppler; (3) Magnetic resonance, magnetic Resonant biliary imaging or spiral CT biliary imaging. If more than two test results indicate a tumor sign, it can be basically diagnosed as hilar cholangiocarcinoma.