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目的评价包头市涂阳肺结核化疗效果,分析影响包头市涂阳肺结核化疗效果的因素。方法选择2005年1月至2009年12月包头市疾病预防控制中心痰涂片阳性的肺结核患者1993例,对性别、年龄、职业、户籍、就诊方式、诊断分型、重症肺结核、治疗分组、治疗方案、有无空洞、粟粒型肺结核、管理方式、转归等13个变量进行逐步回归分析,P<0.05为差异有统计学意义。结果单因素分析显示年龄、职业、户籍、管理方式,其OR值(95%CI值)分别为0.981(0.972~0.990)、0.385(0.190~0.777)、0.235(0.144~0.384)、0.019(0.008~0.047),P值分别为0.000、0.008、0.000、0.000,故年龄、职业、户籍、管理方式为涂阳肺结核化疗效果的影响因素。多因素分析显示年龄、职业、户籍、管理方式、治疗方案、粟粒型肺结核为化疗效果的影响因素,其中年龄(OR值0.989、P值0.037)、职业(OR值2.250、P值0.014)、粟粒型肺结核(OR值0.332、P值0.004)为危险性因素;户籍(OR值0.276、P值0.003)、管理方式(OR值0.010、P值0.000)、治疗方案(OR值10.719、P值0.036)为保护性因素。结论在化疗中对中老年男性、民工、患粟粒型肺结核的患者要高度重视,采取全程督导系统管理模式及高效的化疗方案,提高治愈率,减少复发。
Objective To evaluate the efficacy of smear-positive pulmonary tuberculosis in Baotou and to analyze the factors influencing the efficacy of smear-positive pulmonary tuberculosis in Baotou. Methods 1993 to 2009 December 2009 Baotou Municipal Center for Disease Control and Prevention sputum smear-positive pulmonary tuberculosis patients in 1993 cases of gender, age, occupation, household registration, treatment methods, diagnosis, severe tuberculosis, treatment grouping, treatment Program, whether or not empty, miliary tuberculosis, management, outcome and other 13 variables stepwise regression analysis, P <0.05 for the difference was statistically significant. Results The univariate analysis showed that the OR values (95% CI) were 0.981 (0.972-0.990), 0.385 (0.190-0.777), 0.235 (0.144-0.384), 0.019 0.047), P values were 0.000,0.008,0.000,0.000, so the age, occupation, household registration, management methods for the smear positive pulmonary tuberculosis effect of chemotherapy. Multivariate analysis showed that age, occupation, household registration, management mode, treatment plan and miliary tuberculosis were the influencing factors of chemotherapy effect. Among them, age (OR = 0.989, P = 0.037), occupational (OR = 2.250, P = 0.014) (OR = 0.276, P = 0.003), management (OR = 0.010, P = 0.000), treatment (OR = 10.719, P = 0.036) For protective factors. Conclusions In chemotherapy, we should attach great importance to middle-aged and elderly men, migrant workers and patients with miliary tuberculosis. We should adopt a full supervisory system management model and an effective chemotherapy regimen to improve the cure rate and reduce recurrence.