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目的探讨准分子激光角膜切削术（ＰＲＫ）术后眼压变化规律，皮质类固醇激素对眼压的影响及手术区和非手术区眼压差异情况。方法共随访７２例（１３８眼），其中轻度近视２３例（４４眼），中度近视３５例（６９眼），高度近视１４例（２５眼），于术前及术后２周、１月、２月、３月、４月用非接触式眼压计分别测量手术区（角膜中央）和非手术区（下方角膜周边部）眼压。结果（１）ＰＲＫ术后各阶段眼压普遍低于术前基础眼压，两者有显著性差异（Ｐ＜０．００１）。（２）手术区眼压均低于非手术区眼压，但两者无显著性差异（Ｐ＞０．０５）。（３）激素性高眼压最早出现在术后２周，多在术后３月。结论（１）由于ＮＣＴ本身的局限性可能导致的误差，应对ＰＲＫ术后ＮＣＴ所测的眼压值做综合分析、判断。（２）ＰＲＫ术后应在使用皮质类固醇激素２周开始定期监测眼压。
Objective To investigate the changes of intraocular pressure (IOP) after intraocular lens (PRK) and the effects of corticosteroids on intraocular pressure (IOP) and intraocular pressure (IOP) between surgical and nonoperative areas. Methods A total of 72 patients (138 eyes) were followed up, including 23 mild myopia (44 eyes), 35 moderate myopia (69 eyes) and 14 high myopia (25 eyes) Months, February, March, April IOP were measured intraocular pressure in the surgical area (central cornea) and non-surgical area (lower corneal peripheral portion) with a non-contact tonometer. Results (1) The intraocular pressure in each stage after PRK was generally lower than preoperative baseline intraocular pressure, there was a significant difference (P <0.001). (2) The intraocular pressure in operation area was lower than that in non-operation area, but there was no significant difference (P> 0.05). (3) Hormonal ocular hypertension first appeared in 2 weeks after surgery, mostly in 3 months after surgery. Conclusions (1) Due to the error that may be caused by the limitation of NCT itself, the intraocular pressure measured by NCT after PRK should be comprehensively analyzed and judged. (2) Intraocular pressure should be monitored regularly after 2 weeks of corticosteroid use after PRK.