论文部分内容阅读
深静脉血栓形成危险因素分为环境因素和遗传因素两部分,遗传因素决定了患者在环境因素作用下才会发生深静脉血栓。国内的一些局域统计资料发现我国的深静脉血栓形成的先天性致栓因素为抗凝血酶Ⅲ缺乏、蛋白C缺乏、蛋白S缺乏,尤其蛋白S缺乏可能是我国深静脉血栓的常见原因。这与西方国家的遗传因素不同,后者认为凝血因子Ⅴ突变和凝血酶原基因突变是其常见原因。而高同型半胱氨酸血症和血管紧张素转换酶基因多态性国内外认为均为深静脉血栓的独立危险因素。
Risk factors for deep vein thrombosis is divided into environmental factors and genetic factors in two parts, genetic factors determine the role of environmental factors in patients with deep venous thrombosis. Some domestic statistical data found that China’s deep thrombosis congenital thrombotic factors for the lack of antithrombin Ⅲ, lack of protein C, protein S deficiency, especially protein S deficiency may be a common cause of deep venous thrombosis in China. This is different from the genetic factors in Western countries, the latter that the mutation of coagulation factor Ⅴ and prothrombin gene mutation is its common cause. High homocysteine and angiotensin-converting enzyme gene polymorphism at home and abroad are considered as independent risk factors for deep venous thrombosis.