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目的探讨对重型颅脑损伤患者采用高压氧联合标准脑外伤大骨瓣开颅减压手术的临床疗效。方法选取我院因重度颅脑损伤(GCS≤8分)行手术治疗的患者120例,按照随机分配的原则分为对照组和观察组。其中60例采用标准脑外伤大骨瓣减压手术配合常规治疗的患者作为对照组,另外60例在对照组基础上联合高压氧治疗的患者作为观察组,比较两组患者的临床疗效。结果两组患者治疗前的GCS评分无明显差异(P>0.05);两组患者治疗后的GCS评分均较治疗前升高,且观察组的GCS评分高于对照组(P<0.05)。随访结果显示,观察组患者的GOS评分明显高于对照组,同时预后良好率明显优于对照组患者(P<0.05)。结论标准脑外伤大骨瓣开颅手术的同时联合高压氧治疗,对于降低重型颅脑损伤的重残率、死亡率,提高患者的生存质量具有积极的意义,可在临床治疗中推广使用。
Objective To investigate the clinical effect of decompressive craniectomy using hyperbaric oxygen combined with standard craniocerebral trauma in patients with severe craniocerebral injury. Methods A total of 120 patients underwent surgical treatment of severe craniocerebral injury (GCS≤8) in our hospital were divided into control group and observation group according to the principle of random distribution. Among them, 60 cases were treated with standard traumatic decompressive craniectomy combined with conventional therapy as the control group. Another 60 cases were treated with hyperbaric oxygen on the basis of the control group as the observation group. The clinical efficacy of the two groups was compared. Results There was no significant difference in GCS scores between the two groups before treatment (P> 0.05). GCS scores of both groups were significantly higher than those before treatment, and GCS scores of the observation group were higher than those of the control group (P <0.05). The follow-up results showed that the GOS score of the observation group was significantly higher than that of the control group, and the good prognosis was significantly better than the control group (P <0.05). Conclusions Standard craniotomy with craniocerebral trauma combined with hyperbaric oxygen therapy has positive significance for reducing severe disability and mortality and improving the quality of life of patients with severe traumatic brain injury. It can be used in clinical treatment.